Overview
Alignment is the foundation of most sequence work. We choose the aligner for your data type and scale, and verify the results.
Salient features
- Read mapping and multiple sequence alignment
- Sensitive remote-homology search
- Chromatogram base-calling and trimming
Analyses we offer
Nucleotide sequence alignment
Maps reads or sequences to a reference genome or aligns them against each other, for both short and long reads.
Methods: minimap2, bowtie2, bwa.
Amino acid sequence alignment
Aligns protein sequences and searches for remote homologs to infer function and conserved regions.
Methods: hh-suite, diamond, muscle.
Sanger sequencing
Processes chromatograms, trims low-quality ends, assembles contigs and calls variants from Sanger reads.
Methods: sangeranalyseR, tracy.
What you receive
- A written report with methods, parameters and interpretation
- Processed data tables and publication-quality figures
- Scripts and settings so every result can be reproduced
Not sure which analysis fits your data? Contact us and we will advise.