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Functional Enrichment Analysis

Enrichment analysis for transcriptome, genome, epigenome and metabolome results.

Updated

Overview

Long gene or feature lists become understandable once mapped to pathways, functions and regulatory regions.

Salient features

  • Over-representation and rank-based methods
  • Region-based enrichment for genomic intervals
  • Clear plots and tables

Analyses we offer

Transcriptome data enrichment

Finds pathways and functions enriched among differentially expressed genes.

Methods: clusterProfiler, GSEApy, fgsea.

Genome data enrichment

Tests whether genomic regions are enriched near genes, pathways or annotations.

Methods: ChIPseeker, LOLA, rGREAT.

Epigenome data enrichment

Tests overlap of epigenomic regions with reference annotations and datasets.

Methods: LOLA, rGREAT, giggle.

Metabolome data enrichment

Maps metabolite changes to pathways and enriched metabolic processes.

Methods: MetaboAnalystR, mummichog, FELLA.

What you receive

  • A written report with methods, parameters and interpretation
  • Processed data tables and publication-quality figures
  • Scripts and settings so every result can be reproduced

Not sure which analysis fits your data? Contact us and we will advise.

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